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Pfizer Booster Protection Against Omicron Wanes in Just Weeks, Study Finds

Pfizer Booster Protection Against Omicron Wanes in Just Weeks, Study Finds | 13 May 2022 | Second and third doses of Pfizer's COVID-19 vaccine provide protection against the Omicron variant for only a few weeks, according to peer-reviewed research published today in JAMA Network Open. "Our study found a rapid decline in Omicron-specific serum neutralizing antibody titers only a few weeks after the second and third doses of [the Pfizer-BioNTech] BNT162b2," the authors of the research letter wrote. Danish researchers studied adults who received two or three doses of BNT162b2 between January 2021 and October 2021, or were previously infected prior to February 2021 and then vaccinated. They found that after an initial increase in Omicron-specific antibodies after the second Pfizer shot, levels dropped rapidly, from 76.2% at week 4, to 53.3% at weeks 8 to 10, and 18.9% at weeks 12 to 14.